Endari

Taking ENDARI

Liquid

Your dose of ENDARI may be 1 packet (5 grams), 2 packets (10 grams), or 3 packets (15 grams). Ask your doctor about your prescribed dose.

Your dose of ENDARI is:

1.
2.
3.

Take your prescribed dose of ENDARI twice a day – once in the morning and once in the evening. Each packet of ENDARI is 5 grams.

Morning & Evening

Fill a cup with 8 ounces of liquid. You can use water, milk, apple juice or something similar.

The liquid should be cold or room temperature.

DO NOT USE A HOT LIQUID.

Pour your full dose of ENDARI into the liquid.

Mix your ENDARI with the liquid.

You can still take your ENDARI even if it does not fully dissolve.

Drink the full dose of ENDARI immediately after mixing it.

DO NOT STORE ENDARI MIXTURE FOR LATER

Food

Your dose of ENDARI may be 1 packet (5 grams), 2 packets (10 grams), or 3 packets (15 grams). Ask your doctor about your prescribed dose.

Your dose of ENDARI is:

1.
2.
3.

Take your prescribed dose of ENDARI twice a day – once in the morning and once in the evening. Each packet of ENDARI is 5 grams.

Morning & Evening

Fill a cup or bowl with 4 to 6 ounces of food like yogurt or applesauce.

DO NOT USE A HOT FOOD.

Pour your full dose of ENDARI into the food.

Mix your ENDARI with the food.

You can still take your ENDARI even if it does not fully dissolve.

Eat your full dose of ENDARI immediately after mixing it.

DO NOT STORE ENDARI MIXTURE FOR LATER

INDICATION

ENDARI [L-glutamine oral powder] is indicated to reduce the acute complications of sickle cell disease in adults and children 5 years and older.

IMPORTANT SAFETY INFORMATION

The most common side effects in clinical studies were constipation, nausea, headache, pain in the stomach area, cough, pain in the hands or feet, back pain, and chest pain.

Side effects that led to a stop in treatment during the clinical studies were 1 case each of overactive spleen (an organ that helps filter your blood), pain in the stomach area, indigestion, burning sensation and hot flash.

It is not known whether ENDARI is safe and effective in children younger than 5 years old with sickle cell disease.

Please see full Prescribing Information.

You are encouraged to report all possible negative side effects of ENDARI to Emmaus Medical, Inc. at 1-877-420-6493 or FDA at 1-800-FDA-1080 or www.fda.gov/medwatch.